This episode features Dr. Thomas Greiner PhD from the University of Gothenburg (Sweden), speaking about the various functions of GLP-1 in the gut, and the role of gut microbes in GLP-1 production, with ultimate effects on host health. He noted that GLP-1 is produced by enteroendocrine cells called L-cells, both in the small intestine and […]
https://isappscience.org/wp-content/uploads/2025/07/Greiner-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-07-16 15:54:162025-07-09 17:55:25Unraveling the functions of GLP-1 in the gut, with Dr. Thomas Greiner PhD
We discuss microbes, mucus, and milk with Dr. Clara Belzer PhD from Wageningen University in the Netherlands in this episode. Dr. Belzer, a molecular geneticist, specializes in studying the microorganisms that are equipped to break down the glycans in mucus and human milk within the host environment. Key topics from this episode: Dr. Belzer’s research […]
https://isappscience.org/wp-content/uploads/2025/07/Belzer-highlight-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-07-09 19:06:032025-07-09 18:07:05Archive Highlight: Microbes that break down mucus and milk to benefit the host, with Dr. Clara Belzer PhD
This episode features Dr. Amir Zarrinpar, MD PhD, from UC San Diego (USA) speaking about his work on circadian biology and host metabolism, and what’s currently known about microbial mechanisms. Dr. Zarrinpar explains that in mouse models, restricting feeding to the nocturnal (awake) period is important for their metabolic and overall health. When mice eat […]
https://isappscience.org/wp-content/uploads/2025/07/Zarrinpar-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-07-02 22:11:342025-07-02 22:11:34Investigating the microbial mechanisms contributing to host metabolism, with Dr. Amir Zarrinpar, MD PhD
By Marla Cunningham, ISAPP Executive Director I’m sure you’ve read the results of trials similar to these (fictional) conclusions: ‘Our findings showed an increase in Faecalibacterium and Enterococcus, two groups associated with reduced inflammation, and a decrease in Clostridium spp, which have been associated in previous studies with metabolic risk. These results suggest a beneficial […]
https://isappscience.org/wp-content/uploads/2022/02/ISAPP_LAB_006-scaled.jpg17092560KChttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngKC2025-06-30 16:14:422025-07-10 05:47:35Microbiome endpoints in clinical trials for biotics – where do we stand and what have we learnt?
This episode features Prof. Dirk Haller from Technical University of Munich (Germany) speaking about his work in the field of nutritional immunology, trying to unravel how immunity and gut microbiota interact with metabolism, ultimately impacting the emergence of chronic diseases. He focuses on how microbe-host interactions in the gut impact inflammatory or tumorigenic responses – […]
https://isappscience.org/wp-content/uploads/2025/06/Haller-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-06-27 17:55:402025-06-27 17:55:40Interactions between immunity, gut microbiota, and metabolism, with Prof. Dirk Haller PhD
This episode features Prof. Ben Willing PhD from the University of Alberta, Canada, speaking about his work investigating fermented foods such as kefir for potential cardiometabolic health benefits. The microorganisms associated with fermented foods are not standardized – for example, traditional kefirs have some microorganisms in common, but other microorganisms that are present sporadically. Moreover, kefir […]
https://isappscience.org/wp-content/uploads/2025/06/Willing-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-06-20 17:48:122025-06-23 23:14:17Examining fermented foods for potential cardiometabolic health benefits, with Prof. Ben Willing PhD
This episode features Dr. Karen Corbin PhD RD from AdventHealth Translational Research Institute (USA), speaking about how the triad of diet, gut microbiome, and host characteristics contribute to energy balance as well as metabolic diseases. From the perspective of host physiology, she explores how to use diet to remodel the gut microbiome to impact energy […]
https://isappscience.org/wp-content/uploads/2025/06/Corbin-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-06-11 20:03:222025-06-11 20:03:22Diet and gut microbiome contributions to host energy balance, with Dr. Karen Corbin PhD RD
This episode features Prof. Emad El-Omar MD FRCP from the University of New South Wales in Sydney, Australia, speaking about a recent paper exploring the healthy microbiome concept, as well as the latest research on how the gut microbiome contributes to the pathophysiology of several diseases. Prof. El-Omar talked about research on H. pylori-induced disease […]
https://isappscience.org/wp-content/uploads/2025/06/El-Omar-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-06-04 17:37:062025-06-04 17:37:06Progress in understanding the gut microbiome’s role in health and disease states, with Prof. Emad El-Omar MD FRCP
Biotics, including probiotics and prebiotics, are well known for their human health benefits. But a growing number of studies have focused on biotic use in both agricultural and companion animals. Biotics have been employed in animals to achieve a variety of health benefits as well as improvements in growth and production efficiency. A group of […]
https://isappscience.org/wp-content/uploads/2025/05/chicken-image.jpg7941280KChttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngKC2025-05-29 18:10:332025-05-29 18:10:33Five points to know about biotics for animals, from an ISAPP-led paper
This episode features computational microbiologist Dr. Tarini Ghosh PhD from Indraprastha Institute of Information Technology (Delhi, India) speaking about his recently published paper that proposes a novel Health-Associated Core Keystone (HACK) index for measuring a healthy microbiome. To create the index, the group used a huge volume of sequence data – over 201 terabytes – […]
https://isappscience.org/wp-content/uploads/2025/05/Ghosh-cover.png864864Laurahttps://isappscience.org/wp-content/uploads/2021/06/ISAPP_LogoRedsign_horz.pngLaura2025-05-29 15:31:072025-05-29 15:31:07The HACK index for measuring a health-associated gut microbiome, with Dr. Tarini Ghosh PhD
Unraveling the functions of GLP-1 in the gut, with Dr. Thomas Greiner PhD
/in Podcast, Season Four /by LauraThis episode features Dr. Thomas Greiner PhD from the University of Gothenburg (Sweden), speaking about the various functions of GLP-1 in the gut, and the role of gut microbes in GLP-1 production, with ultimate effects on host health. He noted that GLP-1 is produced by enteroendocrine cells called L-cells, both in the small intestine and […]
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Subscribe: Apple Podcasts | Spotify | RSS
Archive Highlight: Microbes that break down mucus and milk to benefit the host, with Dr. Clara Belzer PhD
/in Podcast, Season Four /by LauraWe discuss microbes, mucus, and milk with Dr. Clara Belzer PhD from Wageningen University in the Netherlands in this episode. Dr. Belzer, a molecular geneticist, specializes in studying the microorganisms that are equipped to break down the glycans in mucus and human milk within the host environment. Key topics from this episode: Dr. Belzer’s research […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS
Investigating the microbial mechanisms contributing to host metabolism, with Dr. Amir Zarrinpar, MD PhD
/in Podcast, Season Four /by LauraThis episode features Dr. Amir Zarrinpar, MD PhD, from UC San Diego (USA) speaking about his work on circadian biology and host metabolism, and what’s currently known about microbial mechanisms. Dr. Zarrinpar explains that in mouse models, restricting feeding to the nocturnal (awake) period is important for their metabolic and overall health. When mice eat […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS
Microbiome endpoints in clinical trials for biotics – where do we stand and what have we learnt?
/in ISAPP Science Blog /by KCBy Marla Cunningham, ISAPP Executive Director I’m sure you’ve read the results of trials similar to these (fictional) conclusions: ‘Our findings showed an increase in Faecalibacterium and Enterococcus, two groups associated with reduced inflammation, and a decrease in Clostridium spp, which have been associated in previous studies with metabolic risk. These results suggest a beneficial […]
Interactions between immunity, gut microbiota, and metabolism, with Prof. Dirk Haller PhD
/in Podcast, Season Four /by LauraThis episode features Prof. Dirk Haller from Technical University of Munich (Germany) speaking about his work in the field of nutritional immunology, trying to unravel how immunity and gut microbiota interact with metabolism, ultimately impacting the emergence of chronic diseases. He focuses on how microbe-host interactions in the gut impact inflammatory or tumorigenic responses – […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS
Examining fermented foods for potential cardiometabolic health benefits, with Prof. Ben Willing PhD
/in Podcast, Season Four /by LauraThis episode features Prof. Ben Willing PhD from the University of Alberta, Canada, speaking about his work investigating fermented foods such as kefir for potential cardiometabolic health benefits. The microorganisms associated with fermented foods are not standardized – for example, traditional kefirs have some microorganisms in common, but other microorganisms that are present sporadically. Moreover, kefir […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS
Diet and gut microbiome contributions to host energy balance, with Dr. Karen Corbin PhD RD
/in Podcast, Season Four /by LauraThis episode features Dr. Karen Corbin PhD RD from AdventHealth Translational Research Institute (USA), speaking about how the triad of diet, gut microbiome, and host characteristics contribute to energy balance as well as metabolic diseases. From the perspective of host physiology, she explores how to use diet to remodel the gut microbiome to impact energy […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS
Progress in understanding the gut microbiome’s role in health and disease states, with Prof. Emad El-Omar MD FRCP
/in Podcast, Season Four /by LauraThis episode features Prof. Emad El-Omar MD FRCP from the University of New South Wales in Sydney, Australia, speaking about a recent paper exploring the healthy microbiome concept, as well as the latest research on how the gut microbiome contributes to the pathophysiology of several diseases. Prof. El-Omar talked about research on H. pylori-induced disease […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS
Five points to know about biotics for animals, from an ISAPP-led paper
/in Uncategorized /by KCBiotics, including probiotics and prebiotics, are well known for their human health benefits. But a growing number of studies have focused on biotic use in both agricultural and companion animals. Biotics have been employed in animals to achieve a variety of health benefits as well as improvements in growth and production efficiency. A group of […]
The HACK index for measuring a health-associated gut microbiome, with Dr. Tarini Ghosh PhD
/in Podcast, Season Four /by LauraThis episode features computational microbiologist Dr. Tarini Ghosh PhD from Indraprastha Institute of Information Technology (Delhi, India) speaking about his recently published paper that proposes a novel Health-Associated Core Keystone (HACK) index for measuring a healthy microbiome. To create the index, the group used a huge volume of sequence data – over 201 terabytes – […]
Podcast: Play in new window | Download
Subscribe: Apple Podcasts | Spotify | RSS