When probiotics guidelines differ: a practical guide for clinicians and researchers

After an expert panel at the ISAPP 2025 annual meeting focused on clinical translation of biotic science, several panel members led the publication of an Editorial in Gut Microbes on how to navigate guidelines from trusted professional societies when they produce differing conclusions about the use of probiotics for gastrointestinal disorders. The article discusses why this issue arises and provides suggestions for helping both researchers and clinicians interpret recommendations that differ. According to the authors, guidelines should be seen as tools to support decision making, rather than providing a definitive answer for all patients.

REFERENCE:

Preidis GA, Szajewska H, Cunningham M, Bauchner H, Merenstein DJ. When probiotics guidelines differ: a practical guide for clinicians and researchers. Gut Microbes. 2026;18(1):2657049.