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Towards optimizing the host response to biotics: a report of an International Scientific Association for Probiotics and Prebiotics working group
In this current era of increased knowledge about mechanisms involving the human gut and its microbiome, the authors discussed whether biotics can be identified as candidates for a specific indication using a more informed, systematic approach. -
Speaker spotlight: Prof. Michael Gänzle on current directions in research on lactobacilli
Prof. Gänzle describes how research on lactobacilli has evolved over the past few decades, including recent developments and future directions. -
Better study design for better probiotic science
ILSI Europe brought together academic researchers and scientists from industry to identify the aspects of probiotic research that are not covered by existing methodological guidance. The result was PRODARE, a consensus framework designed to support better study design, conduct, and reporting in probiotic research. -
Expert insights into skin microbiome research and translation
Skin microbiome research is gaining momentum as researchers uncover its important and unique contributions to health and disease. -
Factors affecting infant gut microbiota development, with Prof. Christopher Stewart PhD
Prof. Christopher Stewart PhD from Newcastle University (UK), speaks about the factors affecting gut microbiota development in both non-preterm and preterm infants. -
Probiotics with antibiotics: Let’s follow the evidence
In this blog, experts address a media article on probiotics with antibiotics and advocate for using evidence instead of weak but plausible-sounding recommendations. -
ISAPP welcomes participation in upcoming one-day scientific symposium in Tokyo
To help meet the goals of accelerating global scientific advancement and showcasing innovative biotics research, ISAPP will hold a scientific symposium on October 6, 2026 in Tokyo, Japan in conjunction with its annual meeting. -
A mechanism linking the newborn skin microbiota to neurodevelopment, with Prof. Rihua Xie and Dr. Yuhang Zhang
Prof. Rihua Xie and Dr. Yuhang Zhang speak about vaginal microbiota transfer (VMT) and how it may affect neurodevelopment in newborn infants born by Cesarean section. -
Gut microbiota development in preterm and non-preterm infants, with Dr. Marie-Claire Arrieta PhD
Dr. Marie-Claire Arrieta PhD from the University of Calgary (Canada), speaks about development of the early life gut microbiome, both in preterm and non-preterm infants. -
When probiotics guidelines differ: a practical guide for clinicians and researchers
Panel members from the ISAPP meeting led the publication of an Editorial in Gut Microbes on how to navigate guidelines from trusted professional societies when they produce differing conclusions about the use of probiotics for gastrointestinal disorders. -
New ISAPP publication sheds light on the translation of probiotic research into clinical guidelines
A new publication titled “When probiotics guidelines differ: a practical guide for clinicians and researchers” addresses why probiotic clinical recommendations may differ and provides suggestions for interpreting recommendations that differ in either subtle or significant ways. -
Toward skin microbiome interventions for anti-aging and wound healing, with Prof. Hariom Yadav PhD
This episode features Prof. Hariom Yadav PhD, from the University of South Florida (USA), speaking about the skin microbiome and potential interventions for anti-aging and wound healing. Prof. Yadav noted that humans have a stable (core) microbiome on the surface of skin cells, plus a transient microbiome that depends on recent exposures. The skin microbiome… -
Alcohol in fermented foods: Considerations for pregnancy and childhood
Typical health recommendations advise not consuming alcohol during pregnancy or during childhood up to the age of 18. Yet some fermented foods contain alcohol. What does the science reveal about resolving this contradiction? -
Biotics, oral microbiota and potential for dental applications
Prof. Seppo Salminen writes that the biotic approach offers potential for new biological intervention strategies in dentistry, aimed at restoring the natural oral microbiota and maintaining the balance by introducing beneficial biotic components into the oral cavity. -
The skin microbiome’s role in atopic dermatitis, with Dr. Maria Teresa García-Romero, MD MPH
Dr. Maria Teresa García-Romero, MD MPH from the National Institute of Pediatrics in Mexico City talks about the skin microbiome and how it relates to atopic dermatitis. -
The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of gut health
A panel of experts evaluated the term gut health in the context of the central role of the gastrointestinal tract in health and overall well-being and proposed a definition of gut health as “a state of normal gastrointestinal function without active gastrointestinal disease and gut-related symptoms that affect quality of life”. -
Fido Needs an Antibiotic: Are There Strategies to Maintain Gut Integrity and Restore Gut Microbiota?
Despite their risks and complications, antimicrobials have their role in managing canine diarrhea and gastrointestinal enteropathies. So, what can be done to minimize the negative effects that they have on stool quality and microbial disruption? -
ISAPP’s scientific consensus definition of gut health
Gut health is a commonly used term that previously had no scientific definition. In the paper, the group defines gut health as: “a state of normal gastrointestinal function without active gastrointestinal disease and gut-related symptoms that affect quality of life”. -
Canada’s Fermented Foods Initiative Hosts Inaugural Workshop: A Cross-Sector Conversation Begins
Toronto hosted the inaugural workshop of the Canadian Fermented Foods Initiative (CFFI), a new effort designed to support and advance research, education and innovation on fermented foods in Canada. -
The 2026 Glenn Gibson Early Career Researcher Award Recipient is Fermented Foods Researcher Dr. Gabriela Fraiz, PhD
The award committee for the 2026 Glenn Gibson Early Career Researcher Award is pleased to announce this year’s winner: Dr. Gabriela Fraiz, PhD, a nutritional science researcher. -
2026 Sanders Award for Advancing Biotic Science Given to Prof. David Mills of UC Davis
The ISAPP board of directors is pleased to announce the selection of the winner of the 2026 Sanders Award for Advancing Biotic Science: Prof. David Mills PhD, a Distinguished Professor and researcher at University of California, Davis, USA. -
What happens when you eat fiber, and why you should eat more
In recent years much research has been done determining that the products of a healthy gut microbiota also have health benefits way beyond the gut. -
Trials on probiotics and prebiotics in infant formula, with Prof. Yvan Vandenplas MD PhD
This episode features Prof. Yvan Vandenplas MD PhD from the University Hospital Brussels and Vrije Universiteit Brussel (Belgium), speaking about the science on probiotics and prebiotics in infant formula. Over the past 20 years in this field, awareness of the importance of the gastrointestinal microbiota has grown, and biotics have been employed to try to… -
Dietary management of chronic constipation, with Dr. Eirini Dimidi PhD RD
This episode features Dr. Eirini Dimidi PhD RD from King’s College London (UK), speaking about the recently published British Dietetic Association’s guidelines for dietary management of chronic constipation. Constipation can be a major concern for patients, but evidence around some of the most common dietary recommendations for addressing it has remained unclear. After a thorough… -
Emerging clinical insights into C. difficile infection from gut microbiota research
In recent years the clinical status and spectrum of C. difficile infection have shifted. The prevalence of this infection has risen sharply. Along with changes that have occurred in the clinical patterns of this disorder, research on the gut microbiome has provided insights into the important factors that contribute to the infection. -
Applying the tools of ecology to manage microbiomes in people with cancer, with Dr. Joao Xavier PhD
This episode features Dr. Joao Xavier PhD, a systems biologist from Memorial Sloan Kettering Cancer Center, speaking about the application of ecological principles and tools to individuals being treated for cancer. His lab combines multi-omics profiling with ecological models to generate insights on how microbes interact with each other, for application to clinical risk prediction… -
Eco-evolutionary processes and antimicrobial resistance in the urobiome, with Dr. Marjon de Vos PhD
This episode features Dr. Marjon de Vos PhD from the University of Groningen (the Netherlands) speaking about microbial ecology and evolution, and in particular how these affect antimicrobial resistance. She studies the urobiome as well as the factors that contribute to urinary tract infections and successful treatment of these infections with antibiotics. Her lab combines… -
Insights into healthy aging: A story as told by gut microbiome (and other) metabolites
Metabolites, including those derived from the gut microbiome, offer a window into the complex biology of aging. They reflect not just how we live, but how well our bodies are adapting to the passage of time. -
Probiotics: NIH Fact Sheet for Health Professionals
This fact sheet from the US National Institutes of Health (NIH) features an overview of probiotics, with scientifically supported health indications as well as safety considerations. -
Highlighted Talks from the 2025 ISAPP Annual Meeting
In this special episode, ISAPP’s Executive Director Marla Cunningham highlights ISAPP’s annual meeting, held in Banff, Canada in July 2025. Four speakers join the podcast to describe their talks from the meeting: Episode abbreviations and links: About our speakers: Carolina Tropini, University of British Columbia, Canada Dr. Carolina Tropini is an Assistant Professor at the… -
ISAPP welcomes two new scientists to its board of directors
The ISAPP board of directors is pleased to welcome two prominent scientists and frequent ISAPP collaborators to its ranks: Prof. Hannah Holscher, PhD, RD from the University of Illinois Urbana-Champaign (USA), and Prof. Jens Walter PhD from University College Cork (Ireland). The appointment of these board members was announced at the recent ISAPP annual meeting in Banff, Canada. -
Five points to know about biotics for animals, from an ISAPP-led paper
A group of animal health experts, comprising academic and industry member scientists convening at the 2023 ISAPP annual meeting, reviewed the evidence on biotics for animals, outlining what’s known to date and the likely future directions in this scientific field.
