Well-informed healthcare professionals know the importance of recommending evidence-based probiotic products to their patients to achieve specific health benefits. But…
We are not convinced that the paper’s authors have justified their recommendation against the use of probiotics in relation to CDI prevention. They fail to clarify why the results of their GRADE evaluation of probiotic evidence for prevention of C. difficile resulted in totally different conclusions compared to the AGA document, which found evidence sufficient for conditional recommendation of four probiotic preparations.